Dalfampridine Extended Release Tablets—Clinical Need and Use

MS presents patients with many challenges, among which walking impairment is one of the most serious. Walking impairment is most prevalent in patients who have had progressive MS for many years, but subtle changes in walking and gait may be discerned even in patients with recent disease onset. These may not be apparent to observers, including healthcare providers, and may not be detectable in a routine physical examination. Decreased walking ability is regarded by most MS patients as the worst consequence of MS and has the most serious impact on their ability to continue in employment and to participate in leisure and social activities. Therefore medications that can help restore walking ability in MS are greatly needed.